Connect with us

Entertainment

FDA approves first pill to treat severe hair loss disorder Alopecia

The US Food and Drug Administration approved the first systemic treatment for severe hair loss disorder Alopecia Areata.

The oral tablet, baricitinib, will treat the entire body rather than just one area, the FDA said in a statement on Monday.

For the latest headlines, follow our Google News channel online or via the app.

Alopecia areata, often referred to as alopecia, is an autoimmune disorder. The body attacks its own hair follicles, causing them to fall out. This usually happens in clumps, with patients losing large patches of hair at a time.

The announcement offers new hope to many who suffer from the disorder, 300,000 of whom live in the US.

“Access to safe and effective treatment options is crucial for the significant number of Americans affected by severe alopecia,” said Director of the Division of Dermatology and Dentistry in the FDA’s Center for Drug Evaluation and Research, Kendall Marcus.

Marcus added that the new treatment “will help fulfill a significant unmet need for patients with severe alopecia areata.”

Olumiant is a Janus kinase (JAK) inhibitor which blocks the activity of one or more of a specific family of enzymes, interfering with the pathway that leads to inflammation. This treatment was already approved for use by the FDA in 2018 as a treatment for rheumatoid arthritis, but more recently, doctors have been using the drug to treat COVID-19 in certain hospitalized adults.

In an attempt to repurpose the drug, researchers tested Olumiant in two randomized, placebo-controlled trials (Trial AA-1 and Trial AA-2) with hundreds of patients who had at least 50 percent scalp hair loss.

Patients in these trials received either a placebo, two milligrams of Olumiant, or four milligrams of Olumiant every day. The primary measurement of efficacy for both trials was the proportion of patients who achieved at least 80 percent scalp hair coverage at week 36.

In Trial AA-1, 22 percent of the 184 patients who received two milligrams of Olumiant and 35 percent of the 281 patients who received four milligrams of Olumiant achieved adequate scalp hair coverage, compared to five percent of the 189 patients who received a placebo, the FDA said.

In Trial AA-2, 17 percent of the 156 patients who received 2 milligrams of Olumiant and 32 percent of the 234 patients who received 4 milligrams of Olumiant achieved adequate scalp hair coverage, compared to 3 percent of the 156 patients who received a placebo.

However, the treatment comes with side effects, some of which include upper respiratory tract infections, acne, high cholesterol, and headaches. Patients could also experience nausea, anemia, weight increase, shingles, and inflammation of hair follicles.

The FDA does not recommend the treatment to be used in conjunction with other JAK inhibitors, biologic immunomodulators, cyclosporine or other potent immunosuppressants.

Read more:

Baby boomers more likely to suffer from multiple chronic health issues than others

Do genetics matter? Cancer not as heritable as once thought, study finds

Over 26 pct rise in US children attempting suicide by poisoning: Report

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Entertainment

ABU DHABI NATIONAL HOTELS PRESENTS SEPTEMBER OFFERS

Experience the true meaning of luxury with Kempinski The Boulevard Dubai and Kempinski
Central Avenue Dubai exclusive UAE residents offer. Get 10% off the best flexible rate, and
enjoy a complimentary breakfast prepared by expert chefs. Delight in luxurious
accommodations, exceptional service and an incredible location with direct access to the
Dubai Mall. Whether you’re looking to indulge in a rejuvenating spa treatment or enjoy a full
day of shopping at one of the world’s largest retail and entertainment destinations, you will
experience a perfect stay at Kempinski The Boulevard Dubai and Kempinski Central Avenue
Dubai

Continue Reading

Entertainment

Arabian Saluki Beauty Contest at ADIHEX 2024: A celebration of ancestral elegance

The Abu Dhabi International Hunting and Equestrian Exhibition (ADIHEX) announce the return of the prestigious Arabian Saluki Beauty Contest, a unique initiative aimed at highlighting the significance of purebred hunting dogs and fostering a connection between the new generation and their rich ancestral heritage.
Under the esteemed patronage of H.H. Sheikh Hamdan bin Zayed Al Nahyan, Ruler’s Representative in Al Dhafra Region and Chairman of the Emirates Falconers’ Club (EFC), this iconic event is scheduled from 31st August to 8th September, 2024, at ADNEC Centre Abu Dhabi, celebrating the blending of deep Emirati cultural traditions with cutting-edge innovation and technology across 11 diverse sectors.
A highlight of this year’s event is the Arabian Saluki Beauty Contest. One of the world’s oldest and most revered dog breeds, the Arabian Saluki stands as a symbol of wild hunting and desert traditions in the Middle East. Known for its grace, speed, and intelligence, this distinctive breed has been a faithful companion to the Bedouin people for over 5,000 years, serving as both a hunter and guardian. The Saluki’s agility and loyalty have made it an integral part of hunting and racing traditions, especially within the Arabian Peninsula.
The Arabian Saluki Centre was established in Abu Dhabi in 2001 alongside the Emirates Falconers’ Club, marking the first facility of its kind in the Arabian Gulf region and the Middle East, to revive the tradition of desert hunting using Saluki dogs, a cherished aspect of desert heritage.
ADIHEX was the first cultural event in the Arab region to honour the bond between Man and his loyal companion, which has been by our side for thousands of years. The Arabian Saluki Beauty Contest is a unique initiative designed to promote interest in purebred hunting dogs and to strengthen the new generation’s connection to their ancestral heritage and traditions and to serve as a testament to this unique bond.
With its origin steeped in history, this fascinating dog’s name is believed to be derived from the city of Saluk in Yemen or the Bani Saluk tribe. Renowned for its endurance and elegance, the Saluki can reach speeds up to 75 kilometres per hour, maintaining this pace over distances up to almost five kilometres. The breed is cherished for its unique physical characteristics, including a slender body, deep chest, long legs, and two distinct coat types: ‘Al Hoss’ (smooth) and ‘Aryash’ (feathery).
The Arabian Saluki Beauty Contest, held during ADIHEX, is more than a beauty pageant. It celebrates the essence of the Saluki by focusing on the dog’s personality, skills, reflexes, and sensory response. Unlike typical dog competitions, this contest evaluates the Saluki’s breed characteristics, behaviour, overall appearance, structure, hunting skills, and psychological traits. Judging criteria include the dog’s gait, head, eyes, mouth, ears, coat, colour, and general impression.
The Arabian Saluki Beauty Contest is an integral part of ADIHEX’s mission to preserve and promote the cultural heritage of the UAE and the wider Arab world. This contest not only showcases the beauty and abilities of the Saluki but also plays a vital role in raising awareness about the importance of preserving traditional hunting practices and the Saluki’s role in them.
This year’s competition will feature four categories: ‘Smooth (Hoss) Males,’ ‘Feathery (Aryash) Males,’ ‘Smooth (Hoss) Females,’ and ‘Feathery (Aryash) Females.’ The event is scheduled to take place during ADIHEX 2024, and, per the rules, participants must ensure their dogs are healthy, microchipped, and vaccinated.
The Saluki’s enduring legacy is celebrated through this competition, which draws participants and spectators from across the region and beyond. It provides a platform for Saluki enthusiasts to connect, share their passion, and celebrate a breed that has remained virtually unchanged for millennia, reflecting the diverse hunting landscapes and traditions of the Middle East.
Aside from the alluring Arabian Saluki Beauty Contest, as the largest edition of ADIHEX to date, the 21st edition will showcase thousands of brands across 11 diverse sectors, offering a dynamic platform for new business opportunities and captivating audiences of all ages. This exhibition celebrates the thrill of an adventurous outdoor lifestyle, allowing visitors to explore falconry, hunting, equestrian sports, veterinary products, fishing and marine sports, environmental preservation, cultural heritage, arts and crafts, and the latest in technology and innovation across all the represented sectors.

Continue Reading

Entertainment

Sharjah Ruler directs allocation of beach for women in Khorfakkan’s Al Luluyah area

H.H. Dr. Sheikh Sultan bin Muhammad Al Qasimi, Supreme Council Member and Ruler of Sharjah, has ordered the allocation of a 500-metre beach for women in Al Luluyah area of Khorfakkan, providing them with complete privacy. The project will include a service building that includes a cafe, a medical clinic and a prayer room for women. His Highness the Ruler of Sharjah also directed the construction of a pedestrian bridge linking Al Bardi 6 and Al Batha areas in Khorfakkan, to facilitate the movement of citizens, and modifications will be implemented on the internal roads in the Hayawa area.

Continue Reading

Trending